eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| capillary leak syndrome | ||||
| Disease ID | 1594 |
|---|---|
| Disease | capillary leak syndrome |
| Definition | A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE. |
| Synonym | acute vascular leak syndrome avls capillary leak syndrome (disorder) capillary leak syndrome [disease/finding] capillary leak syndromes capillary leaking syndrome clarkson disease systemic capillary leak syndrome |
| Orphanet | |
| DOID | |
| UMLS | C0343084 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:14) C0021400 | influenza | 2 C0376545 | hematological malignancies | 1 C0034063 | pulmonary edema | 1 C0022660 | acute renal failure | 1 C0019100 | dengue hemorrhagic fever | 1 C0006309 | brucellosis | 1 C0007785 | cerebral infarction | 1 C0026691 | kawasaki disease | 1 C0007785 | cerebral infarct | 1 C0042769 | virus infection | 1 C0009492 | compartment syndrome | 1 C0035078 | renal failure | 1 C0024302 | large cell lymphoma | 1 C0206180 | anaplastic large cell lymphoma | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:22) 11093 | ADAMTS13 | 1.832 | DISEASES 55811 | ADCY10 | 1.069 | DISEASES 238 | ALK | 1.463 | DISEASES 716 | C1S | 1.284 | DISEASES 720 | C4A | 1.915 | DISEASES 721 | C4B | 1.769 | DISEASES 833 | CARS | 1.122 | DISEASES 930 | CD19 | 1.222 | DISEASES 1378 | CR1 | 1.272 | DISEASES 2214 | FCGR3A | 1.971 | DISEASES 2524 | FUT2 | 1.175 | DISEASES 3440 | IFNA2 | 1.248 | DISEASES 3456 | IFNB1 | 1.255 | DISEASES 3586 | IL10 | 1.027 | DISEASES 4038 | LRP4 | 1.974 | DISEASES 23762 | OSBP2 | 2.204 | DISEASES 10622 | POLR3G | 3.246 | DISEASES 56963 | RGMA | 1.722 | DISEASES 6238 | RRBP1 | 1.776 | DISEASES 7124 | TNF | 1.9 | DISEASES 7171 | TPM4 | 2.299 | DISEASES 7422 | VEGFA | 1.592 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1594 |
|---|---|
| Disease | capillary leak syndrome |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0002615 | Low blood pressure | 4 HP:0000969 | Dropsy | 2 HP:0012398 | Peripheral edema | 1 HP:0001919 | Acute renal failure | 1 HP:0100806 | Sepsis | 1 HP:0100598 | Pulmonary oedema | 1 HP:0000083 | Renal insufficiency | 1 HP:0002202 | Pleural effusion | 1 HP:0001945 | Fever | 1 |
| Disease ID | 1594 |
|---|---|
| Disease | capillary leak syndrome |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:3) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
| Disease ID | 1594 |
|---|---|
| Disease | capillary leak syndrome |
| Case | (Waiting for update.) |